A full-size SUV is primarily a space-and-capability choice: a large body can offer a substantial passenger cabin, useful luggage space, and configuration-dependent towing capability. A hybrid SUV is defined by its engine-and-electric-drive system. It may be small, midsize, or full-size, so the two descriptions are not alternatives by themselves.
For a buyer who needs full-size space, the first task is to establish which vehicles meet the complete carrying requirement. Hybrid propulsion can then be compared within that shortlist. Choosing a smaller hybrid to save fuel is a different compromise from choosing a full-size hybrid instead of a conventional full-size model.